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CAS 211915-84-3

ethyl 3-(2-(((4-cyanophenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate

Codes: DABI-007

Application context (from source-drug indications)

Venous thromboembolismDabigatran Etexilate MesylateEmbolismDabigatran Etexilate MesylateStrokeDabigatran Etexilate MesylateIschaemic strokeDabigatran Etexilate MesylatePulmonary embolismDabigatran Etexilate MesylateVenous thrombosisDabigatran Etexilate Mesylate

Source drugs (routes using this intermediate)

DrugTierExpiry
Dabigatran Etexilate MesylateTier B — Position early-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Dabigatran Etexilate MesylateOriginator routesteps: 7total yield: 0.61g
Dabigatran Etexilate MesylateOptimised routesteps: 9total yield: 44 g
4-(methylamino)-3-nitrobenzoic acid→4-(methylamino)-3-nitrobenzoyl chloride→ethyl 3-(pyridin-2-ylamino)propanoate→ethyl 3-(4-(methylamino)-3-nitro-N-(pyridin-2-yl)benzamido)propanoate→ethyl 3-(3-amino-4-(methylamino)-N-(pyridin-2-yl)benzamido)propanoate→2-((4-cyanophenyl)amino)acetic acid→ethyl 3-(2-(((4-cyanophenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate→hexyl carbonochloridate→4-chloro-3-nitrobenzoic acid→4-chlorobenzoic acid→ethyl 3-(2-(((4-(ethoxy(imino)methyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate→ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate oxalate

Intermediates available on this site

Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.

SupplierProductPrice bandMOQLead timeQualificationsAction
Qualified Partner — East China API WorksDabigatran etexilate mesylate
Pharmaceutical Intermediates
On requestOn requestOn request
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Unibest Nantong cGMP Siteethyl N-[3-amino-4-(methylamino)benzoyl]-N-pyridin-2-yl-beta-alaninate
Pharmaceutical Intermediates
On requestOn requestOn request
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Unibest Taizhou GMP-like SiteN-(4-cyanophenyl)-Glycine
Pharmaceutical Intermediates
On requestOn requestOn request
—

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.