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CAS 221446-45-3
3-Ethyl 5-methyl 2-[(2-chloroethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Codes: Levamlodipine Besylate-006
Application context (from source-drug indications)
HypertensionLevamlodipine BesylateAngina pectorisLevamlodipine BesylateEssential hypertensionLevamlodipine Besylate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Levamlodipine Besylate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
3-Ethyl 5-methyl 2-[(2-chloroethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate→5-Ethyl 3-methyl 4-(2-chlorophenyl)-2-methyl-6-[(2-nitroethoxy)methyl]-1,4-dihydropyridine-3,5-dicarboxylate→(±)-2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine→Ethyl 4-(2-phthalimidoethoxy)acetoacetate→3-Amino-2-butenoic acid methyl ester→2-Chlorobenzaldehyde→3-Ethyl 5-methyl (4RS)-4-(2-chlorophenyl)-2-[[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethoxy]methyl]-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
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