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CAS 223397-73-7
1-benzyl-4-formylpyridin-1-ium bromide
Codes: DONE-020
Application context (from source-drug indications)
Alzheimer's diseaseMemantine Hydrochloride/Donepezil HydrochlorideLewy body dementiaDonepezil HydrochlorideAlzheimer's diseaseDonepezil HydrochlorideDementiaDonepezil HydrochlorideMemory impairmentDonepezil HydrochlorideMild cognitive impairmentDonepezil HydrochlorideOsteoporosisDonepezil Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Memantine Hydrochloride/Donepezil Hydrochloride | Tier C — Watch / trade | - |
| Donepezil Hydrochloride | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
5,6-dimethoxy-2,3-dihydro-1H-inden-1-one→isonicotinaldehyde→(bromomethyl)benzene→1-benzyl-4-formylpyridin-1-ium bromide→(E)-1-benzyl-4-((5,6-dimethoxy-1-oxo-1H-inden-2(3H)-ylidene)methyl)pyridin-1-ium bromide→(E)-2-((1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
5,6-dimethoxy-2,3-dihydro-1H-inden-1-one→isonicotinaldehyde→(bromomethyl)benzene→1-benzyl-4-formylpyridin-1-ium bromide→(E)-1-benzyl-4-((5,6-dimethoxy-1-oxo-1H-inden-2(3H)-ylidene)methyl)pyridin-1-ium bromide→(E)-2-((1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
Intermediates available on this site
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