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CAS 2293093-91-9

(2-Amino-3,5-dibromophenyl)methyl 1H-imidazole-1-carboxylate

Codes: Ambroxol- 031

Application context (from source-drug indications)

Chronic bronchitisRoxithromycin/Ambroxol HydrochlorideBronchitisRoxithromycin/Ambroxol HydrochlorideRespiratory tract infectionRoxithromycin/Ambroxol HydrochloridePneumoniaRoxithromycin/Ambroxol HydrochlorideTracheitisRoxithromycin/Ambroxol HydrochlorideBacterial infectionRoxithromycin/Ambroxol HydrochlorideAnaesthesiaAmbroxol HydrochloridePharyngitisAmbroxol HydrochlorideRespiratory diseaseAmbroxol HydrochlorideBronchitisAmbroxol HydrochlorideParkinson's diseaseAmbroxol HydrochlorideParkinsonismAmbroxol Hydrochloride

Source drugs (routes using this intermediate)

DrugTierExpiry
Roxithromycin/Ambroxol HydrochlorideTier C — Watch / trade-
Ambroxol HydrochlorideTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Roxithromycin/Ambroxol HydrochlorideOptimised routesteps: 5total yield: 35.12g(Ambroxol)
3,5-Dibromo-2-nitrobenzaldehyde→trans-4-(2-Nitro-3,5-dibromobenzylideneamino)cyclohexanol→(2-Amino-3,5-dibromophenyl)methyl 1H-imidazole-1-carboxylate→o-Nitrobenzaldehyde→trans-4-Aminocyclohexanol→2-Amino-3,5-dibromo-N-(trans-4-hydroxycyclohexyl)benzylamine
Ambroxol HydrochlorideOptimised routesteps: 5total yield: 35.12g(Ambroxol)
3,5-Dibromo-2-nitrobenzaldehyde→trans-4-(2-Nitro-3,5-dibromobenzylideneamino)cyclohexanol→(2-Amino-3,5-dibromophenyl)methyl 1H-imidazole-1-carboxylate→o-Nitrobenzaldehyde→trans-4-Aminocyclohexanol→2-Amino-3,5-dibromo-N-(trans-4-hydroxycyclohexyl)benzylamine

Intermediates available on this site

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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.