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CAS 24228-40-8

ethyl 1-benzylpiperidine-4-carboxylate

Codes: DONE-003

Application context (from source-drug indications)

Alzheimer's diseaseMemantine Hydrochloride/Donepezil HydrochlorideLewy body dementiaDonepezil HydrochlorideAlzheimer's diseaseDonepezil HydrochlorideDementiaDonepezil HydrochlorideMemory impairmentDonepezil HydrochlorideMild cognitive impairmentDonepezil HydrochlorideOsteoporosisDonepezil Hydrochloride

Source drugs (routes using this intermediate)

DrugTierExpiry
Memantine Hydrochloride/Donepezil HydrochlorideTier C — Watch / trade-
Donepezil HydrochlorideTier B — Position early-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Memantine Hydrochloride/Donepezil HydrochlorideOriginator routesteps: 5total yield: 0.36 g
ethyl piperidine-4-carboxylate→(chloromethyl)benzene→ethyl 1-benzylpiperidine-4-carboxylate→(1-benzylpiperidin-4-yl)methanol→1-benzylpiperidine-4-carbaldehyde→5,6-dimethoxy-2,3-dihydro-1H-inden-1-one→(E)-2-((1-benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
Donepezil HydrochlorideOriginator routesteps: 5total yield: 0.36 g
ethyl piperidine-4-carboxylate→(chloromethyl)benzene→ethyl 1-benzylpiperidine-4-carboxylate→(1-benzylpiperidin-4-yl)methanol→1-benzylpiperidine-4-carbaldehyde→5,6-dimethoxy-2,3-dihydro-1H-inden-1-one→(E)-2-((1-benzylpiperidin-4-yl)methylene)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

Intermediates available on this site

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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.