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CAS 261787-69-3
N-(4-(4-bromo-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide
Codes: CONI-008
Application context (from source-drug indications)
HyponatraemiaConivaptan HydrochlorideAcute decompensated heart failureConivaptan HydrochlorideHeart failureConivaptan HydrochlorideLiver diseaseConivaptan HydrochlorideTraumatic brain injuryConivaptan HydrochlorideKidney diseaseConivaptan Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Conivaptan Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one→4-nitrobenzoyl chloride→1-(4-nitrobenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one→1-(4-aminobenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one→[1,1'-biphenyl]-2-carboxylic acid→N-(4-(5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide→acetimidamide hydrochloride→N-(4-(4-bromo-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide
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