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CAS 29509-07-7
ethyl 2-chloro-4,4-dimethyl-3-oxopentanoate
Codes: PLIN-006
Application context (from source-drug indications)
Non-small cell lung cancerPlinabulinNeutropeniaPlinabulinMultiple myelomaPlinabulinLung cancerPlinabulinSmall cell lung cancerPlinabulinMerkel细胞癌Plinabulin
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Plinabulin | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1,4-diacetylpiperazine-2,5-dione→benzaldehyde→5-(tert-butyl)-1H-imidazole-4-carbaldehyde→ethyl 4,4-dimethyl-3-oxopentanoate→ethyl 2-chloro-4,4-dimethyl-3-oxopentanoate→formamide→ethyl 5-(tert-butyl)-1H-imidazole-4-carboxylate→(5-(tert-butyl)-1H-imidazol-4-yl)methanol→(Z)-1-acetyl-3-((5-(tert-butyl)-1H-imidazol-4-yl)methylene)piperazine-2,5-dione
Intermediates available on this site
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