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CAS 3034-94-4

1-ethynyl-3-nitrobenzene

Codes: ICOT-025

Application context (from source-drug indications)

Non-small cell lung cancerIcotinib HydrochlorideLung adenocarcinomaIcotinib HydrochlorideBronchial neoplasmIcotinib HydrochlorideLung cancerIcotinib HydrochlorideMetastatic breast cancerIcotinib HydrochloridePsoriasisIcotinib Hydrochloride

Source drugs (routes using this intermediate)

DrugTierExpiry
Icotinib HydrochlorideTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Icotinib HydrochlorideOptimised routesteps: 3total yield: /
3-ethynylaniline→(E)-3-(3-nitrophenyl)acrylic acid→(2S,3R)-2,3-dibromo-3-(3-nitrophenyl)propanoic acid→1-ethynyl-3-nitrobenzene

Intermediates available on this site

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