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CAS 30925-89-4
(1'S,2S,10'R,11'S,15'S)-5'-methoxy-15'-methylspiro[oxirane-2,14'-tetracyclo[8.7.0.0(2,7).0(11,15)]heptadecane]-2'(7'),4'-diene
Codes: (III)90248-2-a
Application context (from source-drug indications)
ContraceptionDienogest/Estradiol ValerateMenorrhagiaDienogest/Estradiol ValerateContraceptive useDienogest/Estradiol ValeratePelvic painDienogest/Estradiol ValerateHeadacheDienogest/Estradiol ValerateDysmenorrhoeaDienogest/Estradiol ValerateContraceptionDienogestEndocrine system disorderDienogestEndometriosisDienogestAdenomyosisDienogestPainDienogest
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Dienogest/Estradiol Valerate | Tier C — Watch / trade | - |
| Dienogest | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
3-Methoxyestra-2,5(10)-dien-17-one→dimethyl(methylidene)-sulfane→(1'S,2S,10'R,11'S,15'S)-5'-methoxy-15'-methylspiro[oxirane-2,14'-tetracyclo[8.7.0.0(2,7).0(11,15)]heptadecane]-2'(7'),4'-diene→2-(17beta-Hydroxy-3-methoxyestra-2,5(10)-dien-17-yl)acetonitrile→2-[(1S,10R,11S,14R,15S)-14-hydroxy-15-methyl-5-oxotetracyclo[8.7.0.0(2,7).0(11,15)]heptadec-2(7)-en-14-yl]acetonitrile→3,3-Dimethoxyestra-5,9-dien-17-one→3-Ethoxyestra-3,5,9-trien-17-one→Acetonitrile anhydrous
3-Methoxyestra-2,5(10)-dien-17-one→dimethyl(methylidene)-sulfane→(1'S,2S,10'R,11'S,15'S)-5'-methoxy-15'-methylspiro[oxirane-2,14'-tetracyclo[8.7.0.0(2,7).0(11,15)]heptadecane]-2'(7'),4'-diene→2-(17beta-Hydroxy-3-methoxyestra-2,5(10)-dien-17-yl)acetonitrile→2-[(1S,10R,11S,14R,15S)-14-hydroxy-15-methyl-5-oxotetracyclo[8.7.0.0(2,7).0(11,15)]heptadec-2(7)-en-14-yl]acetonitrile→3,3-Dimethoxyestra-5,9-dien-17-one→3-Ethoxyestra-3,5,9-trien-17-one→Acetonitrile anhydrous
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