CAS 3342-78-7

(2-Aminophenyl)acetic acid

Codes: (I)91353-8-a, Bromfenac Sodium-044

Application context (from source-drug indications)

Back painDiclofenac Sodium/Eperisone HydrochlorideOsteoarthritisDiclofenac SodiumRheumatoid arthritisDiclofenac SodiumAnkylosing spondylitisDiclofenac SodiumCommon bile duct diseaseDiclofenac SodiumDental pulp diseaseDiclofenac SodiumArthritisDiclofenac SodiumInflammatory diseaseBromfenac SodiumPostoperative painBromfenac Sodium眼睛发炎Bromfenac Sodium眼睛疼痛Bromfenac SodiumDry eye syndromeBromfenac Sodium黄斑水肿Bromfenac Sodium

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Diclofenac Sodium/Eperisone Hydrochloride	Tier C — Watch / trade	-
Diclofenac Sodium	Tier C — Watch / trade	-
Bromfenac Sodium	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Diclofenac Sodium/Eperisone HydrochlorideOptimised routesteps: 3total yield: /

(2-Aminophenyl)acetic acid→Methyl (2-aminophenyl)acetate→Methyl [2-(2-bromopropanamido)phenyl]acetate→2,6-Dichlorophenol→2-[2-(2,6-Dichlorophenylamino)phenyl]acetic acid

Diclofenac SodiumOptimised routesteps: 3total yield: /

(2-Aminophenyl)acetic acid→Methyl (2-aminophenyl)acetate→Methyl [2-(2-bromopropanamido)phenyl]acetate→2,6-Dichlorophenol→2-[2-(2,6-Dichlorophenylamino)phenyl]acetic acid

Bromfenac SodiumOptimised routesteps: 5total yield: 27.9g(Bromfenac Sodium (API))

(2-Aminophenyl)acetic acid→(2-Acetamidophenyl)acetic acid→(2-Acetamido-5-sulfophenyl)acetic acid→4-Bromobenzoyl chloride→[2-Acetamido-3-(4-bromobenzoyl)-5-sulfophenyl]acetic acid→[2-Amino-3-(4-bromobenzoyl)phenyl]acetic acid

Intermediates available on this site

No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.