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CAS 338990-31-1
(2-(((1-chloroethoxy)carbonyl)(methyl)amino)pyridin-3-yl)methyl 2-((tert-butoxycarbonyl)(methyl)amino)acetate
Codes: ISAV-015
Application context (from source-drug indications)
Mucorales infectionIsavuconazonium SulfateAspergillus infectionIsavuconazonium SulfateCryptosporidiosisIsavuconazonium SulfateFungal infectionIsavuconazonium Sulfate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Isavuconazonium Sulfate | Tier C — Watch / trade | 2029 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
methyl (R)-2-hydroxypropanoate→(R)-2-hydroxy-1-morpholinopropan-1-one→(2R)-1-morpholino-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one→2-bromo-1,4-difluorobenzene→(2R)-1-(2,5-difluorophenyl)-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one→2-((1R)-1-(2-(2,5-difluorophenyl)oxiran-2-yl)ethoxy)tetrahydro-2H-pyran→1H-1,2,4-triazole→(3R)-2-(2,5-difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol→(2R,3R)-2-(2,5-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol→1-(((2R,3S)-2-(2,5-difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole→(2S,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile→(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide→4-(2-bromoacetyl)benzonitrile→4-(2-((2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl)thiazol-4-yl)benzonitrile→(2-(((1-chloroethoxy)carbonyl)(methyl)amino)pyridin-3-yl)methyl 2-((tert-butoxycarbonyl)(methyl)amino)acetate→4-(1-(((3-((2-((tert-butoxycarbonyl)(methyl)amino)acetoxy)methyl)pyridin-2-yl)(methyl)carbamoyl)oxy)ethyl)-1-((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-1H-1,2,4-triazol-4-ium chloride→2-chloronicotinic acid→2-chloronicotinoyl chloride→tert-butyl 2-chloronicotinate→tert-butyl 2-(methylamino)nicotinate→(2-(methylamino)pyridin-3-yl)methanol→1-chloroethyl carbonochloridate
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | (2-(((1-Chloroethoxy)carbonyl)(methyl)amino)pyridin-3-yl)methyl 2-((tert-butoxycarbonyl)(methyl)amino)acetate Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.