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CAS 345288-55-3
1-[4-(Benzyloxy)-3-nitrophenyl]-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethanol
Codes: Formoterol Fumarate-016
Application context (from source-drug indications)
AsthmaBudesonide/Formoterol fumarate/Glycopyrronium BromideChronic obstructive pulmonary diseaseBudesonide/Formoterol fumarate/Glycopyrronium BromideChronic obstructive pulmonary diseaseFormoterol Fumarate/GlycopyrrolateChronic obstructive pulmonary diseaseFormoterol FumarateEmphysemaFormoterol FumarateAsthmaFormoterol FumarateBronchitisFormoterol FumarateDiabetic nephropathyFormoterol FumarateBronchospasmFormoterol Fumarate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Budesonide/Formoterol fumarate/Glycopyrronium Bromide | Tier B — Position early | - |
| Formoterol Fumarate/Glycopyrrolate | Tier C — Watch / trade | - |
| Formoterol Fumarate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Budesonide/Formoterol fumarate/Glycopyrronium BromideOptimised routesteps: 1total yield: 150mg(Formoterol Fumarate-017)
1-[4-(Benzyloxy)-3-nitrophenyl]-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethanol→N-[2-(Benzyloxy)-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide
Formoterol Fumarate/GlycopyrrolateOptimised routesteps: 1total yield: 150mg(Formoterol Fumarate-017)
1-[4-(Benzyloxy)-3-nitrophenyl]-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethanol→N-[2-(Benzyloxy)-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide
1-[4-(Benzyloxy)-3-nitrophenyl]-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethanol→N-[2-(Benzyloxy)-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide
Intermediates available on this site
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