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CAS 3543-74-6
ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
Codes: BENDAM-017
Application context (from source-drug indications)
B-cell lymphomaBendamustine HydrochlorideNon-Hodgkin lymphomaBendamustine HydrochlorideChronic lymphocytic leukaemiaBendamustine HydrochlorideMantle cell lymphomaBendamustine HydrochlorideLymphomaBendamustine HydrochlorideMultiple myelomaBendamustine Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Bendamustine Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-chloroethan-1-ol→2-chloro-5-nitroaniline→dihydro-2H-pyran-2,6(3H)-dione→5-((2-chloro-5-nitrophenyl)amino)-5-oxopentanoic acid→5-((2-(methylamino)-5-nitrophenyl)amino)-5-oxopentanoic acid→ethyl 4-(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoate→ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate→ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
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