CAS 3543-75-7

Codes: Bendamustine Hydrochloride

Application context (from source-drug indications)

B-cell lymphomaBendamustine HydrochlorideNon-Hodgkin lymphomaBendamustine HydrochlorideChronic lymphocytic leukaemiaBendamustine HydrochlorideMantle cell lymphomaBendamustine HydrochlorideLymphomaBendamustine HydrochlorideMultiple myelomaBendamustine Hydrochloride

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Bendamustine Hydrochloride	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Bendamustine HydrochlorideOriginator routesteps: 3total yield: 2.2 g

isopropyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate→2-chloroethan-1-ol→isopropyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate→isopropyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate→Bendamustine Hydrochloride

Intermediates available on this site

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