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CAS 35661-39-3
(((9H-fluoren-9-yl)methoxy)carbonyl)-L-alanine
Codes: SAFI-005
Application context (from source-drug indications)
Parkinson's diseaseSafinamide MesylatePainSafinamide MesylateDrug-induced dyskinesiaSafinamide MesylateHepatic function declineSafinamide MesylateMultiple system atrophySafinamide MesylateRenal impairmentSafinamide Mesylate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Safinamide Mesylate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(((9H-fluoren-9-yl)methoxy)carbonyl)-L-alanine→(S)-(9H-fluoren-9-yl)methyl (1-(methylamino)-1-oxopropan-2-yl)carbamate→(S)-2-amino-N-methylpropanamide→4-((triisopropylsilyl)oxy)benzaldehyde→(S,E)-N-methyl-2-((4-((triisopropylsilyl)oxy)benzylidene)amino)propanamide→(S)-N-methyl-2-((4-((triisopropylsilyl)oxy)benzyl)amino)propanamide→(S)-2-((4-hydroxybenzyl)amino)-N-methylpropanamide→(3-fluorophenyl)methanol→(S)-2-((4-((3-fluorobenzyl)oxy)benzyl)amino)-N-methylpropanamide
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