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CAS 36916-18-4
11-chloro-3-methyl-8-phenyl-2,4,5-triazatricyclo[7.4.0.0(2,6)]trideca-1(9),3,5,7,10,12-hexaene
Codes: Alprazolam-004
Application context (from source-drug indications)
AnxietyParoxetine/AlprazolamDepressionParoxetine/AlprazolamAnxiety disorderAlprazolamPanic disorderAlprazolamAnxietyAlprazolamEpilepsyAlprazolamType 1 diabetesAlprazolamSubstance-related disorderAlprazolam
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Paroxetine/Alprazolam | Tier C — Watch / trade | - |
| Alprazolam | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1,1,1-Triethoxyethane→2,6-dichloro-4-phenylquinoline→6-chloro-2-hydrazinyl-4-phenylquinoline→11-chloro-3-methyl-8-phenyl-2,4,5-triazatricyclo[7.4.0.0(2,6)]trideca-1(9),3,5,7,10,12-hexaene→4-(2-benzoyl-4-chlorophenyl)-5-methyl-4H-1,2,4-triazole-3-carbaldehyde→4-(2-benzoyl-4-chlorophenyl)-3-methyl-1,2,4-triazole→1-[5-Chloro-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl]phenyl]-1-phenylmethanone→4-(2-benzoyl-4-chlorophenyl)-3-(bromomethyl)-5-methyl-4H-1,2,4-triazole
1,1,1-Triethoxyethane→2,6-dichloro-4-phenylquinoline→6-chloro-2-hydrazinyl-4-phenylquinoline→11-chloro-3-methyl-8-phenyl-2,4,5-triazatricyclo[7.4.0.0(2,6)]trideca-1(9),3,5,7,10,12-hexaene→4-(2-benzoyl-4-chlorophenyl)-5-methyl-4H-1,2,4-triazole-3-carbaldehyde→4-(2-benzoyl-4-chlorophenyl)-3-methyl-1,2,4-triazole→1-[5-Chloro-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl]phenyl]-1-phenylmethanone→4-(2-benzoyl-4-chlorophenyl)-3-(bromomethyl)-5-methyl-4H-1,2,4-triazole
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