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CAS 37709-42-5

1-Methyl-2-oxocyclohexane-1-carbaldehyde

Codes: (V)101438-76-a

Application context (from source-drug indications)

Breast cancerPaclitaxel/Encequidar mesylateAdenocarcinomaPaclitaxel/Encequidar mesylateAngiosarcomaPaclitaxel/Encequidar mesylateSolid tumourPaclitaxel/Encequidar mesylatePancreatic cancerPaclitaxelNon-small cell lung cancerPaclitaxelHodgkin's diseasePaclitaxelSeminomaPaclitaxelOvarian cancerPaclitaxelBreast cancerPaclitaxel

Source drugs (routes using this intermediate)

DrugTierExpiry
Paclitaxel/Encequidar mesylateTier C — Watch / trade-
PaclitaxelTier B — Position early-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Paclitaxel/Encequidar mesylateOptimised routesteps: 4total yield: /
5-Hexenyl bromide→1-Phenyltetrazoline-5-thione→5-[(Hex-5-en-1-yl)sulfanyl]-1-phenyl-1H-tetrazole→5-(Hex-5-ene-1-sulfonyl)-1-phenyl-1H-tetrazole→1-Methyl-2-oxocyclohexane-1-carbaldehyde→2-Methyl-2-(octa-1,7-dien-1-yl)cyclohexan-1-one→2,4,6-Triisopropylbenzenesulfonohydrazide→N'-[2-Methyl-2-(octa-1,7-dien-1-yl)cyclohexylidene]-2,4,6-tri(propan-2-yl)benzene-1-sulfonohydrazide
PaclitaxelOptimised routesteps: 4total yield: /
5-Hexenyl bromide→1-Phenyltetrazoline-5-thione→5-[(Hex-5-en-1-yl)sulfanyl]-1-phenyl-1H-tetrazole→5-(Hex-5-ene-1-sulfonyl)-1-phenyl-1H-tetrazole→1-Methyl-2-oxocyclohexane-1-carbaldehyde→2-Methyl-2-(octa-1,7-dien-1-yl)cyclohexan-1-one→2,4,6-Triisopropylbenzenesulfonohydrazide→N'-[2-Methyl-2-(octa-1,7-dien-1-yl)cyclohexylidene]-2,4,6-tri(propan-2-yl)benzene-1-sulfonohydrazide

Intermediates available on this site

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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.