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CAS 37731-72-9

(2R,3S,4S,5R)-2-(6-amino-9H-purin-9-yl)-4-bromo-5-(((2,4,4-trimethyl-5-oxo-1,3-dioxolan-2-yl)oxy)methyl)tetrahydrofuran-3-yl acetate

Codes: CORD-003

Application context (from source-drug indications)

淋巴细胞减少症CordycepinSolid tumourCordycepinLymphocytic leukaemiaCordycepinLeukaemiaCordycepin

Source drugs (routes using this intermediate)

DrugTierExpiry
CordycepinTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

CordycepinOptimised routesteps: 3total yield: 36 g
(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol→1-bromo-3-methyl-1-oxobutan-2-yl acetate→(2R,3S,4S,5R)-2-(6-amino-9H-purin-9-yl)-4-bromo-5-(((2,4,4-trimethyl-5-oxo-1,3-dioxolan-2-yl)oxy)methyl)tetrahydrofuran-3-yl acetate→(2R,3S,4R,5R)-2-(6-amino-9H-purin-9-yl)-4-bromo-5-(hydroxymethyl)tetrahydrofuran-3-ol

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