← Back to patent-cliff list
CAS 37763-23-8
D-p-yHdroxyphenylglycine methyl ester
Codes: Amoxicillin-012
Application context (from source-drug indications)
Helicobacter pylori infectionAmoxicillin/Omeprazole/RifabutinDyspepsiaAmoxicillin/Omeprazole/RifabutinDuodenal ulcerRabeprazole Sodium/Metronidazole/AmoxicillinImmune thrombocytopenic purpuraRabeprazole Sodium/Metronidazole/AmoxicillinGastric ulcerRabeprazole Sodium/Metronidazole/AmoxicillinGastritisRabeprazole Sodium/Metronidazole/AmoxicillinHelicobacter pylori infectionRabeprazole Sodium/Metronidazole/AmoxicillinMarginal zone B-cell lymphomaClarithromycin/Rabeprazole Sodium/AmoxicillinDuodenal ulcerClarithromycin/Rabeprazole Sodium/AmoxicillinImmune thrombocytopenic purpuraClarithromycin/Rabeprazole Sodium/AmoxicillinGastric ulcerClarithromycin/Rabeprazole Sodium/AmoxicillinGastritisClarithromycin/Rabeprazole Sodium/AmoxicillinHelicobacter pylori infectionClarithromycin/Rabeprazole Sodium/AmoxicillinBacterial infectionAmoxicillin Sodium
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Amoxicillin/Omeprazole/Rifabutin | Tier C — Watch / trade | - |
| Rabeprazole Sodium/Metronidazole/Amoxicillin | Tier C — Watch / trade | - |
| Clarithromycin/Rabeprazole Sodium/Amoxicillin | Tier C — Watch / trade | - |
| Amoxicillin Sodium | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Methyl glyoxylate→(S)-(-)-1-Phenylethylamine→(1S)-1-(2-Naphthyl)ethanamine→Methyl (2Z)-[[(1S)-1-phenylethyl]imino]acetate→Methyl (2Z)-[[(1S)-1-(naphthalen-2-yl)ethyl]imino]acetate→Carbolic acid→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate hydrogen chloride (1/1)→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate hydrogen chloride (1/1)→D-p-Hydroxyphenylglycine methyl ester hydrochloride→D-p-yHdroxyphenylglycine methyl ester→(+)-6-Aminopenicillanic acid
(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid potassium salt→(2S-(2alpha,5alpha,6beta))-3,3-Dimethyl-7-oxo-6-((phenylacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid→D-p-Hydroxyphenylglycine methyl ester hydrochloride→D-p-yHdroxyphenylglycine methyl ester→(2R)-2-Amino-2-(4-hydroxyphenyl)acetamide
Methyl glyoxylate→(S)-(-)-1-Phenylethylamine→(1S)-1-(2-Naphthyl)ethanamine→Methyl (2Z)-[[(1S)-1-phenylethyl]imino]acetate→Methyl (2Z)-[[(1S)-1-(naphthalen-2-yl)ethyl]imino]acetate→Carbolic acid→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate hydrogen chloride (1/1)→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate hydrogen chloride (1/1)→D-p-Hydroxyphenylglycine methyl ester hydrochloride→D-p-yHdroxyphenylglycine methyl ester→(+)-6-Aminopenicillanic acid
(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid potassium salt→(2S-(2alpha,5alpha,6beta))-3,3-Dimethyl-7-oxo-6-((phenylacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid→D-p-Hydroxyphenylglycine methyl ester hydrochloride→D-p-yHdroxyphenylglycine methyl ester→(2R)-2-Amino-2-(4-hydroxyphenyl)acetamide
Methyl glyoxylate→(S)-(-)-1-Phenylethylamine→(1S)-1-(2-Naphthyl)ethanamine→Methyl (2Z)-[[(1S)-1-phenylethyl]imino]acetate→Methyl (2Z)-[[(1S)-1-(naphthalen-2-yl)ethyl]imino]acetate→Carbolic acid→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate hydrogen chloride (1/1)→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate hydrogen chloride (1/1)→D-p-Hydroxyphenylglycine methyl ester hydrochloride→D-p-yHdroxyphenylglycine methyl ester→(+)-6-Aminopenicillanic acid
(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid potassium salt→(2S-(2alpha,5alpha,6beta))-3,3-Dimethyl-7-oxo-6-((phenylacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid→D-p-Hydroxyphenylglycine methyl ester hydrochloride→D-p-yHdroxyphenylglycine methyl ester→(2R)-2-Amino-2-(4-hydroxyphenyl)acetamide
Methyl glyoxylate→(S)-(-)-1-Phenylethylamine→(1S)-1-(2-Naphthyl)ethanamine→Methyl (2Z)-[[(1S)-1-phenylethyl]imino]acetate→Methyl (2Z)-[[(1S)-1-(naphthalen-2-yl)ethyl]imino]acetate→Carbolic acid→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate→Methyl (2R)-(4-hydroxyphenyl)[(1-phenylethyl)amino]acetate hydrogen chloride (1/1)→Methyl (2R)-(4-hydroxyphenyl)[[1-(naphthalen-2-yl)ethyl]amino]acetate hydrogen chloride (1/1)→D-p-Hydroxyphenylglycine methyl ester hydrochloride→D-p-yHdroxyphenylglycine methyl ester→(+)-6-Aminopenicillanic acid
(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid potassium salt→(2S-(2alpha,5alpha,6beta))-3,3-Dimethyl-7-oxo-6-((phenylacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid→D-p-Hydroxyphenylglycine methyl ester hydrochloride→D-p-yHdroxyphenylglycine methyl ester→(2R)-2-Amino-2-(4-hydroxyphenyl)acetamide
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.