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CAS 4101-30-8

1-(2-amino-4,5-dimethoxyphenyl)ethanone

Codes: CABO-003

Application context (from source-drug indications)

Neuroendocrine tumourCabozantinib S-malatePancreatic neuroendocrine tumourCabozantinib S-malateRenal cell carcinomaCabozantinib S-malateHepatocellular carcinomaCabozantinib S-malateThyroid cancerCabozantinib S-malateNeuroendocrine carcinomaCabozantinib S-malate

Source drugs (routes using this intermediate)

DrugTierExpiry
Cabozantinib S-malateTier B — Position early2029

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Cabozantinib S-malateOriginator routesteps: 7total yield: 3.2 g
1-(3,4-dimethoxyphenyl)ethan-1-one→1-(4,5-dimethoxy-2-nitrophenyl)ethanone→1-(2-amino-4,5-dimethoxyphenyl)ethanone→ethyl formate→6,7-dimethoxyquinolin-4-ol→6,7-dimethoxyquinolin-4-yl trifluoromethanesulfonate→N-(4-fluorophenyl)-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide→cyclopropane-1,1-dicarboxylic acid→4-fluoroaniline→methyl 1-((4-fluorophenyl)carbamoyl)cyclopropanecarboxylate→4-aminophenol

Intermediates available on this site

Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.

SupplierProductPrice bandMOQLead timeQualificationsAction
Unibest Nantong cGMP Site4-Hydroxy-6,7-dimethoxyqunioline
Pharmaceutical Intermediates
On requestOn requestOn request
—
Unibest Taizhou GMP-like Site4-((6,7-Dimethoxyquinolin -4-yl)oxy)aniline
Pharmaceutical Intermediates
On requestOn requestOn request
—
Qualified Partner — East China API Works1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid
Pharmaceutical Intermediates
On requestOn requestOn request
—

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.