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CAS 41202-77-1
1-(2,3-dichlorophenyl)piperazine
Codes: CARI-016
Application context (from source-drug indications)
Major depressive disorderCariprazine HydrochlorideSchizophreniaCariprazine HydrochlorideManiaCariprazine Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Cariprazine Hydrochloride | Tier A — Act now | 2029 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
dimethylcarbamic chloride→4-aminocyclohexanone→1,1-dimethyl-3-(4-oxocyclohexyl)urea→ethyl 2-(diethoxyphosphoryl)acetate→ethyl 2-(4-(3,3-dimethylureido)cyclohexylidene)acetate→ethyl 2-((1r,4r)-4-(3,3-dimethylureido)cyclohexyl)acetate→3-((1r,4r)-4-(2-hydroxyethyl)cyclohexyl)-1,1-dimethylurea→1,1-dimethyl-3-((1r,4r)-4-(2-oxoethyl)cyclohexyl)urea→1-(2,3-dichlorophenyl)piperazine
tert-butyl ((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)carbamate→1-(2,3-dichlorophenyl)piperazine→2-(4-nitrophenyl)acetic acid→ethyl 2-((1r,4r)-4-aminocyclohexyl)acetate hydrochloride→ethyl 2-((1r,4r)-4-((tert-butoxycarbonyl)amino)cyclohexyl)acetate→tert-butyl ((1r,4r)-4-(2-hydroxyethyl)cyclohexyl)carbamate→(1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexanamine→N-((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)-1H-imidazole-1-carboxamide
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Qualified Partner — East China API Works | 1-(2,3-Dichlorophenyl)-piperazine hydrochloride Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.