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CAS 439133-67-2
(S)-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine (S)-2-hydroxy-2-phenylacetate
Codes: ROTI-006
Application context (from source-drug indications)
Restless legs syndromeRotigotineParkinson's diseaseRotigotineSubstance-related disorderRotigotineDrug-related adverse effects and reactionsRotigotineTissue adhesionsRotigotinePostoperative painRotigotine
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Rotigotine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
naphthalene-1,6-diol→1,6-dimethoxynaphthalene→5-methoxy-3,4-dihydronaphthalen-2(1H)-one→5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine→(S)-2-hydroxy-2-phenylacetic acid→(S)-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine (S)-2-hydroxy-2-phenylacetate→(S)-5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine→2-(thiophen-2-yl)ethyl 4-methylbenzenesulfonate→(S)-5-methoxy-N-(2-(thiophen-2-yl)ethyl)-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride→propionic acid→(S)-5-methoxy-N-propyl-N-(2-(thiophen-2-yl)ethyl)-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | (S)-2-Amino-5-methoxytetralin (S)-mandelate Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.