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CAS 4453-90-1
1,4-dihydro-1,4-methanonaphthalene
Codes: VARE-002
Application context (from source-drug indications)
Nicotine dependenceVarenicline TartrateNicotine withdrawalVarenicline TartrateSmoking cessationVarenicline TartrateSmoking reductionVarenicline TartrateCannabis dependenceVarenicline TartrateNebulisationVarenicline Tartrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Varenicline Tartrate | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(7,8-diamino-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one→2,2,2-trifluoro-1-(6,7,9,10-tetrahydro-8H-6,10-methanoazepino[4,5-g]quinoxalin-8-yl)ethan-1-one→1-bromo-2-fluorobenzene→1,4-dihydro-1,4-methanonaphthalene→1,2,3,4-tetrahydro-1,4-methanonaphthalene-2,3-diol→3-benzyl-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine→2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine→2,2,2-trifluoro-1-(1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)ethan-1-one→1-(7,8-dinitro-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 1,4-DIHYDRO-1,4-METHANONAPHTHALENE Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.