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CAS 471295-99-5
(Z)-5-(4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzylidene)thiazolidine-2,4-dione
Codes: PIOG-019
Application context (from source-drug indications)
Type 2 diabetesAlogliptin Benzoate/Pioglitazone HydrochlorideType 2 diabetesPioglitazone HydrochloridePulmonary hypertensionPioglitazone HydrochlorideBreast cancerPioglitazone HydrochlorideNon-alcoholic steatohepatitisPioglitazone HydrochlorideCocaine addictionPioglitazone HydrochlorideAlcohol abusePioglitazone Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Alogliptin Benzoate/Pioglitazone Hydrochloride | Tier C — Watch / trade | - |
| Pioglitazone Hydrochloride | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
thiazolidine-2,4-dione→4-hydroxybenzaldehyde→5-ethyl-2-vinylpyridine→2-bromo-1-(5-ethylpyridin-2-yl)ethan-1-ol→4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzaldehyde→(Z)-5-(4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzylidene)thiazolidine-2,4-dione→5-(4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzyl)thiazolidine-2,4-dione→5-(4-(2-chloro-2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione
thiazolidine-2,4-dione→4-hydroxybenzaldehyde→5-ethyl-2-vinylpyridine→2-bromo-1-(5-ethylpyridin-2-yl)ethan-1-ol→4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzaldehyde→(Z)-5-(4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzylidene)thiazolidine-2,4-dione→5-(4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzyl)thiazolidine-2,4-dione→5-(4-(2-chloro-2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione
Intermediates available on this site
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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.