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CAS 480439-89-2
(2R,3R,4R,5R)-2-((benzoyloxy)methyl)-5-(4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diyl dibenzoate
Codes: TRIC-003
Application context (from source-drug indications)
LeukaemiaTriciribine PhosphateBreast cancerTriciribine PhosphateOvarian cancerTriciribine PhosphateHaematological malignancyTriciribine PhosphateSolid tumourTriciribine Phosphate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Triciribine Phosphate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine→(2S,3R,4R,5R)-2-acetoxy-5-((benzoyloxy)methyl)tetrahydrofuran-3,4-diyl dibenzoate→(2R,3R,4R,5R)-2-((benzoyloxy)methyl)-5-(4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diyl dibenzoate→(2R,3R,4R,5R)-2-((benzoyloxy)methyl)-5-(4-chloro-5-cyano-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diyl dibenzoate→methylhydrazine→(2R,3R,4R,5R)-2-((benzoyloxy)methyl)-5-(5-cyano-4-(1-methylhydrazineyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diyl dibenzoate→(2R,3R,4S,5R)-2-(3-amino-5-methyl-1,4,5,6,8-pentaazaacenaphthylen-1(5H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
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