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CAS 482375-18-8
N1-((1S,2R,4S)-2-amino-4-(dimethylcarbamoyl)cyclohexyl)-N2-(5-chloropyridin-2-yl)oxalamide
Codes: EDOX-039
Application context (from source-drug indications)
Pulmonary embolismEdoxaban Tosilate HydrateVenous thromboembolismEdoxaban Tosilate HydrateStrokeEdoxaban Tosilate HydrateEmbolismEdoxaban Tosilate HydrateVenous thrombosisEdoxaban Tosilate HydrateIschaemic strokeEdoxaban Tosilate Hydrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Edoxaban Tosilate Hydrate | Tier B — Position early | 2028 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
tert-butyl ((1R,2S,5S)-2-azido-5-(dimethylcarbamoyl)cyclohexyl)carbamate→lithium 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylate→sodium 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate→tert-butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate→tert-butyl ((1R,2S,5S)-2-(2-((5-chloropyridin-2-yl)amino)-2-oxoacetamido)-5-(dimethylcarbamoyl)cyclohexyl)carbamate→N1-((1S,2R,4S)-2-amino-4-(dimethylcarbamoyl)cyclohexyl)-N2-(5-chloropyridin-2-yl)oxalamide
Intermediates available on this site
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