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CAS 498-94-2
piperidine-4-carboxylic acid
Codes: LASM-001, BALI-006
Application context (from source-drug indications)
MigraineLasmiditan hemisuccinateDrug-related adverse effects and reactionsLasmiditan hemisuccinateUrticariaBilastineAllergic rhinitisBilastineDermatitisBilastinePruritusBilastineEczemaBilastineAllergic conjunctivitisBilastine
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Lasmiditan hemisuccinate | Tier C — Watch / trade | - |
| Bilastine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
piperidine-4-carboxylic acid→1-methylpiperidine-4-carboxylic acid→1-methylpiperidine-4-carbonyl chloride hydrochloride→N,N,1-trimethylpiperidine-4-carboxamide→2,6-dibromopyridine→(6-bromopyridin-2-yl)(1-methylpiperidin-4-yl)methanone→(6-aminopyridin-2-yl)(1-methylpiperidin-4-yl)methanone→2,4,6-trifluorobenzoyl chloride
benzene-1,2-diamine→piperidine-4-carboxylic acid→2-(piperidin-4-yl)-1H-benzo[d]imidazole→tert-butyl 4-(1H-benzo[d]imidazol-2-yl)piperidine-1-carboxylate→2-ethoxyethyl methanesulfonate→tert-butyl 4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidine-1-carboxylate→1-(2-ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole→ethyl 2-methyl-2-(4-(2-((methylsulfonyl)oxy)ethyl)phenyl)propanoate→ethyl 2-(4-(2-(4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)-2-methylpropanoate→2-(4-bromophenyl)ethan-1-ol→((1-ethoxy-2-methylprop-1-en-1-yl)oxy)trimethylsilane→ethyl 2-(4-(2-hydroxyethyl)phenyl)-2-methylpropanoate
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 2-Piperidin-4-yl-1H-benzoimidazole Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | tert-butyl 4-(1H-benzo[d]iMidazol-2-yl)piperidine-1-carboxylate Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | 1-(2-Ethoxy-ethyl)-2-piperidin-4-yl-1H-benzimidazole Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Nantong cGMP Site | 4-(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenethyl 4-methylbenzenesulfonate Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.