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CAS 503068-37-9
(R)-2-((6-(2-((2,6-dichlorobenzyl)oxy)ethoxy)hexyl)amino)-1-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)ethan-1-ol
Codes: VILA-007
Application context (from source-drug indications)
AsthmaVilanterol TrifenatateChronic obstructive pulmonary diseaseVilanterol Trifenatate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Vilanterol Trifenatate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
N-methoxy-N-methylacetamide→1-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)ethan-1-one→2-bromo-1-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)ethan-1-one→VILA-014→tert-butyl (2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-oxoethyl)carbamate→tert-butyl (R)-(2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-hydroxyethyl)carbamate→2-(bromomethyl)-1,3-dichlorobenzene→2-((2,6-dichlorobenzyl)oxy)ethan-1-ol→1,6-dibromohexane→2-((2-((6-bromohexyl)oxy)ethoxy)methyl)-1,3-dichlorobenzene→(R)-5-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)oxazolidin-2-one→(R)-3-(6-(2-((2,6-dichlorobenzyl)oxy)ethoxy)hexyl)-5-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)oxazolidin-2-one→(R)-2-((6-(2-((2,6-dichlorobenzyl)oxy)ethoxy)hexyl)amino)-1-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)ethan-1-ol→2,2,2-triphenylacetic acid→4-bromo-2-(hydroxymethyl)phenol→6-bromo-2,2-dimethyl-4H-benzo[d][1,3]dioxine
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