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CAS 506-03-6
(S)-3-(hexadecyloxy)propane-1,2-diol
Codes: CI-201-003
Application context (from source-drug indications)
COVID-19VB-201HIV infectionVB-201Cardiac and vascular disordersVB-201Inflammatory diseaseVB-201Ulcerative colitisVB-201PsoriasisVB-201
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| VB-201 | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-bromohexadecane→(R)-(2,2-dimethyl-1,3-dioxolan-4-yl)methanol→(S)-3-(hexadecyloxy)propane-1,2-diol→(R)-1-(hexadecyloxy)-3-(trityloxy)propan-2-ol→hex-5-en-1-yl methanesulfonate→(R)-((2-(hex-5-en-1-yloxy)-3-(hexadecyloxy)propoxy)methanetriyl)tribenzene→(S)-2-(hex-5-en-1-yloxy)-3-(hexadecyloxy)propan-1-ol→2-bromoethyl phosphorodichloridate→(R)-2-(hex-5-en-1-yloxy)-3-(hexadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate→(R)-3-(hexadecyloxy)-2-((5-oxopentyl)oxy)propyl (2-(trimethylammonio)ethyl) phosphate
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