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CAS 52523-35-0
N-(trimethylsilyl)-4-((trimethylsilyl)oxy)-1,3,5-triazin-2-amine
Codes: DECI-010, AZAC-006
Application context (from source-drug indications)
Allergic reactionDecitabineCycloplegiaDecitabineHypotensionDecitabineAcute myeloid leukaemiaDecitabineMyelodysplastic syndromeDecitabineDiffuse large B-cell lymphomaDecitabine幼年型粒单核细胞白血病AzacitidineAcute myeloid leukaemiaAzacitidineMyelodysplastic syndromeAzacitidineChronic myeloid leukaemiaAzacitidineChronic myelomonocytic leukaemiaAzacitidine脑性瘫痪Azacitidine
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Decitabine | Tier C — Watch / trade | - |
| Azacitidine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(3S,4R)-3,4,5-trihydroxypentanal→(2R,3R,5R)-2-(hydroxymethyl)-5-methoxytetrahydrofuran-3-ol→((2R,3S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)oxy)-5-methoxytetrahydrofuran-2-yl)methyl ((9H-fluoren-9-yl)methyl) carbonate→((2R,3S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)oxy)-5-chlorotetrahydrofuran-2-yl)methyl ((9H-fluoren-9-yl)methyl) carbonate→N-(trimethylsilyl)-4-((trimethylsilyl)oxy)-1,3,5-triazin-2-amine→trimethylsilyl trifluoromethanesulfonate→((2R,3S,5R)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)oxy)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-2-yl)methyl ((9H-fluoren-9-yl)methyl) carbonate→4-amino-1,3,5-triazin-2(1H)-one
N-(trimethylsilyl)-4-((trimethylsilyl)oxy)-1,3,5-triazin-2-amine→4-amino-1,3,5-triazin-2(1H)-one→trimethylsilyl (E)-N-(trimethylsilyl)acetimidate→(4S,5R)-5-(acetoxymethyl)tetrahydrofuran-2,4-diyl diacetate
4-amino-1,3,5-triazin-2(1H)-one→N-(trimethylsilyl)-4-((trimethylsilyl)oxy)-1,3,5-triazin-2-amine→(2S,3R,4R,5R)-5-(acetoxymethyl)tetrahydrofuran-2,3,4-triyl triacetate→(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(2-oxo-4-((trimethylsilyl)amino)-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate
4-amino-1,3,5-triazin-2(1H)-one→N-(trimethylsilyl)-4-((trimethylsilyl)oxy)-1,3,5-triazin-2-amine→(2S,3R,4R,5R)-5-(acetoxymethyl)tetrahydrofuran-2,3,4-triyl triacetate→AZAC-009→N-Methylformamide-001→1-(diaminomethylene)urea→(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate
Intermediates available on this site
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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.