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CAS 53617-35-9
4-(piperidin-4-yl)morpholine
Codes: ALEC-009
Application context (from source-drug indications)
Non-small cell lung cancerAlectinib HydrochlorideLung cancerAlectinib Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Alectinib Hydrochloride | Tier B — Position early | 2030 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
7-methoxy-3,4-dihydronaphthalen-2(1H)-one→7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one→6-bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one→3-hydrazinylbenzonitrile→9-bromo-8-methoxy-6,6-dimethyl-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile→9-bromo-8-methoxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile→9-bromo-8-hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile→9-bromo-3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yl trifluoromethanesulfonate→4-(piperidin-4-yl)morpholine→9-bromo-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile→ethynyltriisopropylsilane→9-ethynyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
4-(piperidin-4-yl)morpholine→2-(4-bromophenyl)-2-methylpropanoic acid→potassium trifluoro(vinyl)borate→2-methyl-2-(4-vinylphenyl)propanoic acid→2-(4-ethylphenyl)-2-methylpropanoic acid→2-(4-ethyl-3-iodophenyl)-2-methylpropanoic acid→3-(tert-butoxy)-3-oxopropanoic acid→tert-butyl 4-(4-ethyl-3-iodophenyl)-4-methyl-3-oxopentanoate→4-chloro-3-nitrobenzonitrile→tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate→tert-butyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate hydrochloride→6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic acid
4-(piperidin-4-yl)morpholine→6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylic acid→1-(3-bromo-4-ethylphenyl)ethanone→1-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)ethanone→2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-ol→methyl 6-cyano-1H-indole-3-carboxylate→methyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate→1H-indole-6-carbonitrile→2,2,2-trichloroacetyl chloride
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 4-(piperidin-4-yl)morpholine Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.