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CAS 543737-10-6
4-(3-bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline
Codes: TENAP-006
Application context (from source-drug indications)
HyperphosphataemiaTenapanor hydrochlorideChronic renal impairmentTenapanor hydrochlorideConstipationTenapanor hydrochlorideIrritable bowel syndromeTenapanor hydrochlorideChronic idiopathic constipationTenapanor hydrochlorideCystic fibrosisTenapanor hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Tenapanor hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(3-bromophenyl)ethanone→2-bromo-1-(3-bromophenyl)ethanone→1-(2,4-dichlorophenyl)-N-methylmethanamine→1-(3-bromophenyl)-2-((2,4-dichlorobenzyl)(methyl)amino)ethanone→1-(3-bromophenyl)-2-((2,4-dichlorobenzyl)(methyl)amino)ethanol→4-(3-bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline→(S)-4-(3-bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline→(S)-4-(3-(benzylthio)phenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline→(S)-3-(6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzene-1-sulfonyl chloride hydrochloride→2,2'-(ethane-1,2-diylbis(oxy))diethanamine→TENAP-011→1,4-diisocyanatobutane
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 4-(3-bromophenyl)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinoline Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.