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CAS 56-45-1
(S)-2-Amino-3-hydroxypropanoic acid
Codes: (I)638294-12-a
Application context (from source-drug indications)
Systolic heart failureFinerenoneDiastolic heart failureFinerenoneHeart failureFinerenoneChronic renal impairmentFinerenoneDiabetic nephropathyFinerenoneType 2 diabetesFinerenone
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Finerenone | Tier C — Watch / trade | 2030 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(S)-2-Amino-3-hydroxypropanoic acid→(S)-Ethyl 2-amino-3-hydroxypropanoate hydrochloride→(S)-Ethyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate→2,2-Dimethyl-6-methyl-1,3-dioxin-4-one→(2S)-2-[(tert-Butoxycarbonyl)amino]-3-ethoxy-3-oxopropyl 3-oxobutanoate→2-Methoxy-4-cyanobenzaldehyde→(2S)-2-[(tert-Butoxycarbonyl)amino]-3-ethoxy-3-oxopropyl-2-[(4-cyano-2-methoxyphenyl)methylidene]-3-oxobutanoate→4-Amino-5-methylpyridin-2(1H)-one→(2S)-2-[(tert-Butoxycarbonyl)amino]-3-ethoxy-3-oxopropyl 4-(4-cyano-2-methoxyphenyl)-5-hydroxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylate→(Diethoxymethoxy)ethane→(2S)-2-[(tert-Butoxycarbonyl)amino]-3-ethoxy-3-oxopropyl 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylate→(2S)-2-[(tert-Butoxycarbonyl)amino]-3-ethoxy-3-oxopropyl 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,6-naphthyridine-3-carboxylate→(2S)-2-[(tert-Butoxycarbonyl)amino]-3-ethoxy-3-oxopropyl (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylate
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | L-Serine Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.