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CAS 56-86-0

(S)-(+)-Glutamic acidL-alpha-Aminoglutaric acid

Codes: Folic Acid-052, Reduced Glutathione Sodium-001

Application context (from source-drug indications)

Essential hypertensionEnalapril Maleate/Folic AcidMegaloblastic anaemiaFolic AcidFolate deficiencyFolic AcidNeural tube defectFolic AcidAnaemiaFolic AcidHot flushesFolic AcidHyperhomocysteinaemiaFolic AcidAcute respiratory distress syndromeReduced Glutathione SodiumLiver diseaseReduced Glutathione Sodium酒精性肝炎Reduced Glutathione Sodium酒精性肝硬化Reduced Glutathione Sodium酒精性脂肪肝病Reduced Glutathione SodiumSepsisReduced Glutathione Sodium

Source drugs (routes using this intermediate)

DrugTierExpiry
Enalapril Maleate/Folic AcidTier C — Watch / trade-
Folic AcidTier C — Watch / trade-
Reduced Glutathione SodiumTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Enalapril Maleate/Folic AcidOptimised routesteps: 4total yield: 38.92g(Folic Acid (Free))
4-Nitrobenzoyl chloride→(S)-(+)-Glutamic acid→(2S)-[(4-Nitrobenzoyl)amino]pentanedioic acid→Sodium 1-[[(1S)-1-carboxy-3-carboxylatopropyl]carbamoyl]-4-nitrobenzene→N-(4-Aminobenzoyl)-L-glutamic acid→2,5,6-Triaminopyrimidin-4(5H)-one→2,5,6-Triaminopyrimidin-4-one sulfate→1,1,3-Trichloroacetone
Folic AcidOptimised routesteps: 4total yield: 38.92g(Folic Acid (Free))
4-Nitrobenzoyl chloride→(S)-(+)-Glutamic acid→(2S)-[(4-Nitrobenzoyl)amino]pentanedioic acid→Sodium 1-[[(1S)-1-carboxy-3-carboxylatopropyl]carbamoyl]-4-nitrobenzene→N-(4-Aminobenzoyl)-L-glutamic acid→2,5,6-Triaminopyrimidin-4(5H)-one→2,5,6-Triaminopyrimidin-4-one sulfate→1,1,3-Trichloroacetone
Reduced Glutathione SodiumOptimised routesteps: 1total yield: 224mg(Reduced Glutathione Sodium (Free))

Intermediates available on this site

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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.