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CAS 5708-19-0
(S)-cyclohex-3-ene-1-carboxylic acid
Codes: EDOX-002
Application context (from source-drug indications)
Pulmonary embolismEdoxaban Tosilate HydrateVenous thromboembolismEdoxaban Tosilate HydrateStrokeEdoxaban Tosilate HydrateEmbolismEdoxaban Tosilate HydrateVenous thrombosisEdoxaban Tosilate HydrateIschaemic strokeEdoxaban Tosilate Hydrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Edoxaban Tosilate Hydrate | Tier B — Position early | 2028 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
cyclohex-3-ene-1-carboxylic acid→(S)-cyclohex-3-ene-1-carboxylic acid→(1S,4S,5S)-4-iodo-6-oxabicyclo[3.2.1]octan-7-one→ethyl (1S,3S,6R)-7-oxabicyclo[4.1.0]heptane-3-carboxylate→ethyl (1S,3R,4R)-3-azido-4-hydroxycyclohexane-1-carboxylate→ethyl (1S,3R,4R)-3-((tert-butoxycarbonyl)amino)-4-hydroxycyclohexane-1-carboxylate→ethyl (1S,3R,4S)-4-azido-3-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylate→(1S,3R,4S)-4-azido-3-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylic acid→tert-butyl ((1R,2S,5S)-2-azido-5-(dimethylcarbamoyl)cyclohexyl)carbamate→(1S,3R,4S)-3-amino-4-azido-N,N-dimethylcyclohexane-1-carboxamide→lithium 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylate→N-((1R,2S,5S)-2-azido-5-(dimethylcarbamoyl)cyclohexyl)-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide→N-((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide→sodium 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Qualified Partner — East China API Works | (S)-cyclohex-3-enecarboxylic acid Pharmaceutical Intermediates | On request | On request | On request | — |
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