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CAS 59091-92-8

N-[4-(2-Acetamido-4-oxo-1,4-dihydropteridin-6-ylmethyleneamino)benzoyl]-L-glutamic acid dimethyl diester

Codes: Folic Acid-021

Application context (from source-drug indications)

Essential hypertensionEnalapril Maleate/Folic AcidMegaloblastic anaemiaFolic AcidFolate deficiencyFolic AcidNeural tube defectFolic AcidAnaemiaFolic AcidHot flushesFolic AcidHyperhomocysteinaemiaFolic Acid

Source drugs (routes using this intermediate)

DrugTierExpiry
Enalapril Maleate/Folic AcidTier C — Watch / trade-
Folic AcidTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Enalapril Maleate/Folic AcidOptimised routesteps: 4total yield: /
2-Amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde→N-(6-Formyl-4-oxo-1,4-dihydropteridin-2-yl)acetamide dihydrate→N-(4-Aminobenzoyl)-L-glutamic acid dimethyl diester→N-[4-(2-Acetamido-4-oxo-1,4-dihydropteridin-6-ylmethyleneamino)benzoyl]-L-glutamic acid dimethyl diester→N-[4-(2-Acetamido-4-oxo-1,4-dihydropteridin-6-ylmethylamino)benzoyl]-L-glutamic acid dimethyl diester
Folic AcidOptimised routesteps: 4total yield: /
2-Amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde→N-(6-Formyl-4-oxo-1,4-dihydropteridin-2-yl)acetamide dihydrate→N-(4-Aminobenzoyl)-L-glutamic acid dimethyl diester→N-[4-(2-Acetamido-4-oxo-1,4-dihydropteridin-6-ylmethyleneamino)benzoyl]-L-glutamic acid dimethyl diester→N-[4-(2-Acetamido-4-oxo-1,4-dihydropteridin-6-ylmethylamino)benzoyl]-L-glutamic acid dimethyl diester

Intermediates available on this site

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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.