CAS 6148-64-7

potassium 3-ethoxy-3-oxopropanoate

Codes: SITAF-041, PAZU-026, MONT-046

Application context (from source-drug indications)

CystitisSitafloxacin HydrateSinusitisSitafloxacin HydrateTonsillitisSitafloxacin HydratePneumoniaSitafloxacin HydrateCervicitisSitafloxacin HydratePericoronitisSitafloxacin Hydrate肺炎链球菌感染Pazufloxacin MesylateSepsisPazufloxacin MesylateInfectious diseasePazufloxacin MesylateCystitisPazufloxacin Mesylate胆管炎Pazufloxacin MesylateCholecystitisPazufloxacin MesylateAllergic rhinitisMontelukastAsthmaMontelukastHypersensitivity reactionMontelukastSeasonal allergic rhinitisMontelukastPerennial allergic rhinitisMontelukastExercise-induced asthmaMontelukast

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Sitafloxacin Hydrate	Tier C — Watch / trade	-
Pazufloxacin Mesylate	Tier C — Watch / trade	-
Montelukast	Tier B — Position early	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Sitafloxacin HydrateOptimised routesteps: 8total yield: 383.3 mg

SITAF-007→1,2-dibromoethane→benzylglycine→N-benzyl-N-(tert-butoxycarbonyl)glycine→potassium 3-ethoxy-3-oxopropanoate→ethyl 4-(benzyl(tert-butoxycarbonyl)amino)-3-oxobutanoate→ethyl 1-(N-benzyl-N-(tert-butoxycarbonyl)glycyl)cyclopropane-1-carboxylate→5-benzyl-5-azaspiro[2.4]heptane-4,7-dione→(S)-5-benzyl-7-hydroxy-5-azaspiro[2.4]heptan-4-one→(S)-5-benzyl-5-azaspiro[2.4]heptan-7-amine→tert-butyl (S)-(5-benzyl-5-azaspiro[2.4]heptan-7-yl)carbamate

Pazufloxacin MesylateOptimised routesteps: 11total yield: 39.7 g

(S)-2-aminopropan-1-ol→2,3,4,5-tetrafluorobenzoic acid→tert-butyl 2-cyanoacetate→ethyl 4-(2-(tert-butoxy)-1-cyano-2-oxoethyl)-2,3,5-trifluorobenzoate→ethyl 4-(cyanomethyl)-2,3,5-trifluorobenzoate→4-(1-cyanocyclopropyl)-2,3,5-trifluorobenzoic acid→4-(1-carbamoylcyclopropyl)-2,3,5-trifluorobenzoic acid→4-(1-aminocyclopropyl)-2,3,5-trifluorobenzoic acid→4-(1-acetamidocyclopropyl)-2,3,5-trifluorobenzoic acid→potassium 3-ethoxy-3-oxopropanoate→ethyl 3-(4-(1-acetamidocyclopropyl)-2,3,5-trifluorophenyl)-3-oxopropanoate→ethyl (S)-2-(4-(1-acetamidocyclopropyl)-2,3,5-trifluorobenzoyl)-3-((1-hydroxypropan-2-yl)amino)acrylate→ethyl (S)-10-(1-acetamidocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate→(S)-10-(1-acetamidocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

MontelukastOptimised routesteps: 7total yield: /

3-Methylbenzoic acidm-Toluic acid→3-Methylbenzoic acid methyl ester→methyl 3-(bromomethyl)benzoate→3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]benzoic acid methyl ester→7-Chloro-2-methylquinoline 7-Chloroquinaldine→3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]benzoic acid methyl ester→3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]benzoic acid→3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]benzoyl chloride→potassium 3-ethoxy-3-oxopropanoate

Intermediates available on this site

Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.

Supplier	Product	Price band	MOQ	Lead time	Qualifications	Action
Unibest Nantong cGMP Site	Carbamic acid, (7S)-5-azaspiro[2.4]hept-7-yl-, 1,1-dimethylethyl ester (9CI) Pharmaceutical Intermediates	On request	On request	On request	—

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.