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CAS 619-45-4
Methyl 4-aminobenzoatemethyl 4-aminobenzoate
Codes: Folic Acid-072, ENSAR-009
Application context (from source-drug indications)
Essential hypertensionEnalapril Maleate/Folic AcidMegaloblastic anaemiaFolic AcidFolate deficiencyFolic AcidNeural tube defectFolic AcidAnaemiaFolic AcidHot flushesFolic AcidHyperhomocysteinaemiaFolic AcidNon-small cell lung cancerEnsartinib HydrochlorideLung cancerEnsartinib HydrochlorideBrain metastasesEnsartinib HydrochlorideNon-Hodgkin lymphomaEnsartinib HydrochlorideHepatoblastomaEnsartinib HydrochlorideOsteosarcomaEnsartinib Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Enalapril Maleate/Folic Acid | Tier C — Watch / trade | - |
| Folic Acid | Tier C — Watch / trade | - |
| Ensartinib Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-Cyanoacetic acid ethyl ester→Aminoformamidine hydrochloride→2,4-Diamino-6-hydroxypyrimidine→2,4-Diamino-6-hydroxy-5-nitrosopyrimidine→2,5,6-Triaminopyrimidin-4(5H)-one→2-Propenal→Methyl 4-aminobenzoate→Methyl 4-[[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]benzoate→L-Glutamic acid monosodium salt
2-Cyanoacetic acid ethyl ester→Aminoformamidine hydrochloride→2,4-Diamino-6-hydroxypyrimidine→2,4-Diamino-6-hydroxy-5-nitrosopyrimidine→2,5,6-Triaminopyrimidin-4(5H)-one→2-Propenal→Methyl 4-aminobenzoate→Methyl 4-[[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]benzoate→L-Glutamic acid monosodium salt
3,6-dichloropyridazine→6-chloropyridazin-3-amine→4-bromo-6-chloropyridazin-3-amine→1-(2,6-dichloro-3-fluorophenyl)ethan-1-ol→(R)-6-chloro-4-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridazin-3-amine→ENSAR-006→ENSAR-007→ENSAR-008→methyl 4-aminobenzoate→ENSAR-010→ENSAR-011→(2R,6S)-2,6-dimethylpiperazine→ENSAR-013→1-(2,6-dichloro-3-fluorophenyl)ethan-1-ol
Intermediates available on this site
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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.