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CAS 63-05-8

(3aS,3bR,9aR,9bS,11aS)-9a,11a-Dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-1,7-dione(8R,9S,10R,13S,14S)-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione

Codes: (I)169995-10-a, PRAS-007, PRAS-008, DUTA-026

Application context (from source-drug indications)

ContraceptionDrospirenoneStomatitis, aphthousDrospirenonePremenstrual dysphoric disorderDrospirenonePremenstrual syndromeDrospirenoneDysmenorrhoeaDrospirenoneDepressionDrospirenoneVulvovaginal atrophyPrasteroneAtrophyPrasteroneDyspareuniaPrasteroneBreast cancerPrasteroneVaginal diseasePrasteroneAnal neoplasmPrasteroneBenign prostatic hyperplasiaDutasteride/Tamsulosin HydrochlorideUrinary retentionDutasterideBenign prostatic hyperplasiaDutasterideAlopeciaDutasterideAlcohol abuseDutasterideBladder cancerDutasterideProstate cancerDutasteride

Source drugs (routes using this intermediate)

DrugTierExpiry
DrospirenoneTier C — Watch / trade-
PrasteroneTier C — Watch / trade-
Dutasteride/Tamsulosin HydrochlorideTier C — Watch / trade-
DutasterideTier B — Position early-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

PrasteroneOptimised routesteps: 4total yield: 13.21 g
(8R,9S,10R,13S,14S)-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione

Intermediates available on this site

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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.