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CAS 6630-33-7
ethyl 4-(piperazin-1-yl)benzoate
Codes: ASEN-016, IMIQ-023
Application context (from source-drug indications)
SchizophreniaAsenapine MaleateManiaAsenapine MaleateBipolar I disorderAsenapine MaleateStutteringAsenapine MaleateParanoid schizophreniaAsenapine MaleateDisorganised schizophreniaAsenapine MaleateActinic keratosisImiquimod尖锐湿疣Imiquimod角化病ImiquimodBasal cell carcinomaImiquimod巨大尖锐湿疣Imiquimod人乳头瘤病毒感染Imiquimod
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Asenapine Maleate | Tier C — Watch / trade | - |
| Imiquimod | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
ethyl 4-(piperazin-1-yl)benzoate→(E)-1-bromo-2-(2-nitrovinyl)benzene→methyl 2-(5-chloro-2-methoxyphenyl)acetate→methyl 3-(2-bromophenyl)-2-(5-chloro-2-methoxyphenyl)-4-nitrobutanoate→4-(2-bromophenyl)-3-(5-chloro-2-methoxyphenyl)pyrrolidin-2-one→4-(2-bromophenyl)-3-(5-chloro-2-methoxyphenyl)-1-methylpyrrolidin-2-one→3-(2-bromophenyl)-2-(5-chloro-2-methoxyphenyl)-4-(methylamino)butanoic acid→(3S,4S)-4-(2-bromophenyl)-3-(5-chloro-2-methoxyphenyl)-1-methylpyrrolidin-2-one→(3S,4S)-4-(2-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1-methylpyrrolidin-2-one→(3aS,12bS)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-1-one
2-methylpropan-1-amine→4-chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline→ethyl 4-(piperazin-1-yl)benzoate→ethyl 2-isocyanoacetate→(Z)-ethyl 3-(2-bromophenyl)-2-formamidoacrylate→(E)-ethyl 3-bromo-3-(2-bromophenyl)-2-formamidoacrylate→(E)-ethyl 3-bromo-3-(2-bromophenyl)-2-isocyanoacrylate→ethyl 5-(2-bromophenyl)-1-isobutyl-1H-imidazole-4-carboxylate→5-(2-bromophenyl)-1-isobutyl-1H-imidazole-4-carboxylic acid→5-(2-bromophenyl)-1-isobutyl-1H-imidazole-4-carboxamide→1-isobutyl-1H-imidazo[4,5-c]quinolin-4(5H)-one
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