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CAS 676593-24-1

5,5-Dimethyl-2-(prop-1-en-2-yl)-1,3,2-dioxaborinane

Codes: (XVI)101438-67-b

Application context (from source-drug indications)

Breast cancerPaclitaxel/Encequidar mesylateAdenocarcinomaPaclitaxel/Encequidar mesylateAngiosarcomaPaclitaxel/Encequidar mesylateSolid tumourPaclitaxel/Encequidar mesylatePancreatic cancerPaclitaxelNon-small cell lung cancerPaclitaxelHodgkin's diseasePaclitaxelSeminomaPaclitaxelOvarian cancerPaclitaxelBreast cancerPaclitaxel

Source drugs (routes using this intermediate)

DrugTierExpiry
Paclitaxel/Encequidar mesylateTier C — Watch / trade-
PaclitaxelTier B — Position early-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Paclitaxel/Encequidar mesylateOptimised routesteps: 3total yield: /
2-Isopropenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane→2-Propanal→2,2'-(Propane-2,2-diyl)bis(5,5-dimethyl-1,3,2-dioxaborinane)→5,5-Dimethyl-2-(prop-1-en-2-yl)-1,3,2-dioxaborinane→2,2'-(Propane-2,2-diyl)bis(2H-1,3,2-benzodioxaborole)→2-(Prop-1-en-2-yl)-2H-1,3,2-benzodioxaborole
PaclitaxelOptimised routesteps: 3total yield: /
2-Isopropenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane→2-Propanal→2,2'-(Propane-2,2-diyl)bis(5,5-dimethyl-1,3,2-dioxaborinane)→5,5-Dimethyl-2-(prop-1-en-2-yl)-1,3,2-dioxaborinane→2,2'-(Propane-2,2-diyl)bis(2H-1,3,2-benzodioxaborole)→2-(Prop-1-en-2-yl)-2H-1,3,2-benzodioxaborole

Intermediates available on this site

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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.