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CAS 70958-20-2

2-(5-chloro-2-phenoxyphenyl)acetic acid

Codes: ASEN-001

Application context (from source-drug indications)

SchizophreniaAsenapine MaleateManiaAsenapine MaleateBipolar I disorderAsenapine MaleateStutteringAsenapine MaleateParanoid schizophreniaAsenapine MaleateDisorganised schizophreniaAsenapine Maleate

Source drugs (routes using this intermediate)

DrugTierExpiry
Asenapine MaleateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Asenapine MaleateOriginator routesteps: 6total yield: /
2-(5-chloro-2-phenoxyphenyl)acetic acid→2-(5-chloro-2-phenoxyphenyl)acetyl chloride→methyl methylglycinate→methyl N-(2-(5-chloro-2-phenoxyphenyl)acetyl)-N-methylglycinate→3-(5-chloro-2-phenoxyphenyl)-1-methylpyrrolidine-2,4-dione→11-chloro-2-methyl-2,3-dihydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-1-one→(3aR,12bR)-11-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-1-one→(3aR,12bS)-11-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrol-1-one

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