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CAS 71989-33-8
Fmoc-O-tert-butyl-L-serine
Codes: Tirzepatide-001
Application context (from source-drug indications)
Obstructive sleep apnoea syndromeTirzepatideObesityTirzepatideOverweightTirzepatideType 2 diabetesTirzepatide
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Tirzepatide | Tier B — Position early | 2036 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Fmoc-O-tert-butyl-L-serine→Resin bound O-tert-butyl-L-serinamide→Resin bound L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound Gly-Pro-Pro-Pro-Ser(tBu)-NH→Resin bound O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-prolyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound glycyl-L-prolyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound N-[(2,4-dimethoxyphenyl)methyl]glycylglycyl-L-prolyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-alanyl-N-[(2,4-dimethoxyphenyl)methyl]glycylglycyl-L-prolyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-isoleucyl-L-alanyl-N-[(2,4-dimethoxyphenyl)methyl]glycylglycyl-L-prolyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-leucyl-L-isoleucyl-L-alanyl-N-[(2,4-dimethoxyphenyl)methyl]glycylglycyl-L-prolyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound 1-(tert-butoxycarbonyl)-L-tryptophyl-L-leucyl-L-isoleucyl-L-alanyl-N-[(2,4-dimethoxyphenyl)methyl]glycylglycyl-L-prolyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound N-(triphenylmethyl)-L-glutaminyl-1-(tert-butyloxycarbonyl)-L-tryptophyl-L-leucyl-L-isoleucyl-L-alanyl-N-[(2,4-dimethoxyphenyl)methyl]glycylglycyl-L-prolyl-3-O-tert-butyl-L-seryl-3-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-O-tert-butyl-L-serinamide→Resin bound L-valyl-N-(triphenylmethyl)-L-glutaminyl-1-(tert-butyloxycarbonyl)-L-tryptophyl-L-leucyl-L-isoleucyl-L-alanyl-N-[(2,4-dimethoxyphenyl)methyl]glycylglycyl-L-prolyl-3-O-tert-butyl-L-seryl-3-O-tert-butyl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-3-O-tert-butyl-L-serinamide
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Sichuan Tongsheng Biopharmaceutical Co., Ltd. | Fmoc-Ser(tBu)-OH Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.