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CAS 75-03-6
1-Iodoethane
Codes: (VIII)819703-2-a, (II)638294-3-a, (VII)638294-14-a, (III)115092-6-a, (III)115092-8-a, Atosiban-054, Mosapride Citrate-002
Application context (from source-drug indications)
Gastrointestinal stromal tumourRipretinibSystolic heart failureFinerenoneDiastolic heart failureFinerenoneHeart failureFinerenoneChronic renal impairmentFinerenoneDiabetic nephropathyFinerenoneType 2 diabetesFinerenoneGlaucomaProxodolol hydrochloride/Pilocarpine Hydrochloride闭角型青光眼Pilocarpine HydrochlorideOcular hypertensionPilocarpine HydrochlorideOpen-angle glaucomaPilocarpine Hydrochloride瞳孔缩小Pilocarpine HydrochlorideSjögren's syndromePilocarpine Hydrochloride虹膜炎Pilocarpine Hydrochloride产科分娩（早产）Atosiban acetate早产（孕37周前）Atosiban acetateEndometriosisAtosiban acetateGastritisMosapride CitrateEnteral feeding intoleranceMosapride CitrateIrritable bowel syndromeMosapride CitrateDyspepsiaMosapride CitrateConstipationMosapride Citrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Ripretinib | Tier C — Watch / trade | 2032 |
| Finerenone | Tier C — Watch / trade | 2030 |
| Proxodolol hydrochloride/Pilocarpine Hydrochloride | Tier C — Watch / trade | - |
| Pilocarpine Hydrochloride | Tier C — Watch / trade | - |
| Atosiban acetate | Tier C — Watch / trade | - |
| Mosapride Citrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Methyl (2-bromo-4-fluoro-5-nitrophenyl)acetate→6-Chloro-4-nitropyridine-3-carbaldehyde→Methyl (2Z)-2-(2-bromo-4-fluoro-5-nitrophenyl)-3-(6-chloro-4-nitropyridin-3-yl)prop-2-enoate→3-(5-Amino-2-bromo-4-fluorophenyl)-7-chloro-1,6-naphthyridin-2(1H)-one→Aminobenzene→1,1,1-Trichloromethanol 1,1'-carbonate→N-[4-Bromo-5-(7-chloro-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl]-N'-phenylurea→1-Iodoethane→N-[4-Bromo-5-(7-chloro-1-ethyl-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl]-N'-phenylurea→Aminomethane
4-Amino-5-methylpyridin-2(1H)-one→1-Iodoethane→2-Ethoxy-5-methylpyridin-4-amine→N-(2-Ethoxy-5-methylpyridin-4-yl)-2,2-dimethylpropanamide→2-Methoxy-4-cyanobenzaldehyde→N-[3-[(4-Cyano-2-methoxyphenyl)(hydroxy)methyl]-2-ethoxy-5-methylpyridin-4-yl]-2,2-dimethylpropanamide→4-[(4-Amino-2-ethoxy-5-methylpyridin-3-yl)(hydroxy)methyl]-3-methoxybenzonitrile→3-Oxobutanamide→(±)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide→4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,6-naphthyridine-3-carboxamide→(aS)-10,16-Di(anthracen-9-yl)-13-hydroxy-12,14-dioxa-13lambda5-phosphapentacyclo[13.8.0.02,11.03,8.018,23]tricosa-1(15),2(11),3,5,7,9,16,18,20,22-decaene 13-oxide
4-Bromo-2-methoxybenzaldehyde→3-Oxobutanamide→(2Z)-2-[(4-Bromo-2-methoxyphenyl)methylidene]-3-oxobutanamide→4-Amino-5-methylpyridin-2(1H)-one→4-(4-Bromo-2-methoxyphenyl)-2,5-dihydroxy-2,8-dimethyl-1,2,3,4-tetrahydro-1,6-naphthyridine-3-carboxamide→4-(4-Bromo-2-methoxyphenyl)-5-hydroxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide→1-Iodoethane→4-(4-Bromo-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide→(4S)-4-(4-Bromo-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
(2R)-2-Hydroxysuccinic acid→(R)-2-Hydroxysuccinic acid dimethylester→1-Iodoethane→Diethyl (2S,3R)-2-methyl-3-hydroxysuccinate→Dimethyl (2S,3R)-2-ethyl-3-[(4-nitrobenzene-1-sulfonyl)oxy]butanedioate→Dimethyl (3R)-2-bromo-3-ethylbutanedioate→1-Methyl-1H-imidazole-5-carbaldehyde→Methyl (3S,4S)-4-ethyl-2-(1-methyl-1H-imidazol-5-yl)-5-oxooxolane-3-carboxylate→(2S,3R)-2-Ethyl-4-methoxy-3-[(1-methyl-1H-imidazol-5-yl)methyl]-4-oxobutanoic acid
(2R)-2-Hydroxysuccinic acid→(R)-Diethyl malate→(R)-Diisopropyl 2-hydroxysuccinate→1-Iodoethane→Diethyl (2S,3R)-2-ethyl-3-hydroxybutanedioate→Dipropan-2-yl (2S,3R)-2-ethyl-3-hydroxybutanedioate→Diethyl (2S,3R)-2-ethyl-3-[(4-nitrobenzene-1-sulfonyl)oxy]butanedioate→Dipropan-2-yl (2S,3R)-2-ethyl-3-[(4-nitrobenzene-1-sulfonyl)oxy]butanedioate→Diethyl (3R)-2-bromo-3-ethylbutanedioate→Diisopropyl 2-bromo-3(R)-ethyl-butanedioate
(2R)-2-Hydroxysuccinic acid→(R)-2-Hydroxysuccinic acid dimethylester→1-Iodoethane→Diethyl (2S,3R)-2-methyl-3-hydroxysuccinate→Dimethyl (2S,3R)-2-ethyl-3-[(4-nitrobenzene-1-sulfonyl)oxy]butanedioate→Dimethyl (3R)-2-bromo-3-ethylbutanedioate→1-Methyl-1H-imidazole-5-carbaldehyde→Methyl (3S,4S)-4-ethyl-2-(1-methyl-1H-imidazol-5-yl)-5-oxooxolane-3-carboxylate→(2S,3R)-2-Ethyl-4-methoxy-3-[(1-methyl-1H-imidazol-5-yl)methyl]-4-oxobutanoic acid
(2R)-2-Hydroxysuccinic acid→(R)-Diethyl malate→(R)-Diisopropyl 2-hydroxysuccinate→1-Iodoethane→Diethyl (2S,3R)-2-ethyl-3-hydroxybutanedioate→Dipropan-2-yl (2S,3R)-2-ethyl-3-hydroxybutanedioate→Diethyl (2S,3R)-2-ethyl-3-[(4-nitrobenzene-1-sulfonyl)oxy]butanedioate→Dipropan-2-yl (2S,3R)-2-ethyl-3-[(4-nitrobenzene-1-sulfonyl)oxy]butanedioate→Diethyl (3R)-2-bromo-3-ethylbutanedioate→Diisopropyl 2-bromo-3(R)-ethyl-butanedioate
1-(Bromomethyl)benzene→3-Sulfanylpropanoic acid→Methyl N-[3-(benzylsulfanyl)propanoyl]-D-tyrosinate→3-(Benzylsulfanyl)propanoic acid→3-(Benzylsulfanyl)propanoyl chloride→Methyl D-tyrosinate→2(R)-Amino-3-(4-hydroxyphenyl)propionic acid→1-Iodoethane→Methyl N-[3-(benzylsulfanyl)propanoyl]-O-ethyl-D-tyrosinate→3-(Benzylsulfanyl)-N-[(2R)-3-(4-ethoxyphenyl)-1-hydrazino-1-oxopropan-2-yl]propanamide
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 4-Bromo-2-methoxybenzaldehyde Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | 4-formyl-3-methoxybenzonitrile Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | 4-AMino-5-Methylpyridin-2-ol Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Nantong cGMP Site | 2-chloro-5-methylpyridin-4-amine Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | 2-Cyanoethyl 3-oxobutanoate Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.