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CAS 75130-24-4

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-(2-cyanoethyl)5-methyl ester1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-(2-Cyanoethyl) 5-Methyl E

Codes: Lercanidipine Hydrochloride-036

Application context (from source-drug indications)

Essential hypertensionValsartan/Lercanidipine HydrochlorideHypertensionLercanidipine Hydrochloride

Source drugs (routes using this intermediate)

DrugTierExpiry
Valsartan/Lercanidipine HydrochlorideTier C — Watch / trade-
Lercanidipine HydrochlorideTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Valsartan/Lercanidipine HydrochlorideOptimised routesteps: 5total yield: /
Methyl acetoacetate→3-Hydroxypropionitrile→2-Cyanoethyl 3-oxobutanoate→(E)-2-cyanoethyl 3-aminobut-2-enoate→3-Nitrobenzaldehyde→1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-(2-Cyanoethyl) 5-Methyl E
Lercanidipine HydrochlorideOptimised routesteps: 5total yield: /
Methyl acetoacetate→3-Hydroxypropionitrile→2-Cyanoethyl 3-oxobutanoate→(E)-2-cyanoethyl 3-aminobut-2-enoate→3-Nitrobenzaldehyde→1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 3-(2-Cyanoethyl) 5-Methyl E

Intermediates available on this site

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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.