Unibest
← Back to patent-cliff list

CAS 7719-12-2

Phosphorous chloride

Codes: (IIb)456655-2-a

Application context (from source-drug indications)

Heart failureTolvaptan Sodium Phosphate

Source drugs (routes using this intermediate)

DrugTierExpiry
Tolvaptan Sodium PhosphateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Tolvaptan Sodium PhosphateOptimised routesteps: 2total yield: /
1-[4-(2-Methylbenzoylamino)-2-methylbenzoyl]-7-chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-ol→Pentachloro-lambda5-phosphane→Phosphorous chloride→[7-Chloro-1-[2-methyl-4-[(2-methylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]oxy-hydroxy-oxophosphanium

Intermediates available on this site

No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.