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CAS 79-44-7
dimethylcarbamic chloride
Codes: CARI-008, TOPI-008, TOPI-009
Application context (from source-drug indications)
Major depressive disorderCariprazine HydrochlorideSchizophreniaCariprazine HydrochlorideManiaCariprazine HydrochlorideHyperuricaemiaTopiroxostatGoutTopiroxostatDiabetic nephropathyTopiroxostat
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Cariprazine Hydrochloride | Tier A — Act now | 2029 |
| Topiroxostat | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-bromo-2,3-dichlorobenzene→tert-butyl piperazine-1-carboxylate→tert-butyl 4-(2,3-dichlorophenyl)piperazine-1-carboxylate→1-(2,3-dichlorophenyl)piperazine hydrochloride→tert-butyl ((1r,4r)-4-(2-oxoethyl)cyclohexyl)carbamate→tert-butyl ((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)carbamate→(1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexanamine→dimethylcarbamic chloride
dimethylcarbamic chloride→4-aminocyclohexanone→1,1-dimethyl-3-(4-oxocyclohexyl)urea→ethyl 2-(diethoxyphosphoryl)acetate→ethyl 2-(4-(3,3-dimethylureido)cyclohexylidene)acetate→ethyl 2-((1r,4r)-4-(3,3-dimethylureido)cyclohexyl)acetate→3-((1r,4r)-4-(2-hydroxyethyl)cyclohexyl)-1,1-dimethylurea→1,1-dimethyl-3-((1r,4r)-4-(2-oxoethyl)cyclohexyl)urea→1-(2,3-dichlorophenyl)piperazine
4-cyanopyridine 1-oxide→isonicotinohydrazide→dimethylcarbamic chloride→dimethylcarbamic chloride→5-(2-cyanopyridin-4-yl)-N,N-dimethyl-3-(pyridin-4-yl)-1H-1,2,4-triazole-1-carboxamide
Intermediates available on this site
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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.