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CAS 80223-79-6
2-Methoxy-5-(2-oxopropyl)benzene-1-sulfonyl chloride
Codes: Tamsulosin Hydrochloride-100
Application context (from source-drug indications)
Erectile dysfunctionTadalafil/TamsulosinBenign prostatic hyperplasiaTadalafil/TamsulosinLower urinary tract symptomsSolifenacin Succinate/Tamsulosin HydrochlorideBenign prostatic hyperplasiaSolifenacin Succinate/Tamsulosin HydrochlorideOveractive bladderSolifenacin Succinate/Tamsulosin HydrochlorideDrug-related adverse effects and reactionsSolifenacin Succinate/Tamsulosin HydrochlorideBladder neck obstructionSolifenacin Succinate/Tamsulosin HydrochlorideBenign prostatic hyperplasiaDutasteride/Tamsulosin HydrochlorideBenign prostatic hyperplasiaTamsulosin HydrochlorideUrinary tract infectionTamsulosin HydrochlorideUrinary retentionTamsulosin HydrochlorideInguinal herniaTamsulosin HydrochlorideVoiding dysfunctionTamsulosin HydrochlorideLower urinary tract symptomsTamsulosin Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Tadalafil/Tamsulosin | Tier C — Watch / trade | - |
| Solifenacin Succinate/Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
| Dutasteride/Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
| Tamsulosin Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(4-Methoxyphenyl)acetic acid→1-(4-Methoxyphenyl)-2-propanone→Chloridosulfuric acid→2-Methoxy-5-(2-oxopropyl)benzene-1-sulfonyl chloride→1,1-Dimethylethylamine→N-tert-Butyl-2-methoxy-5-(2-oxopropyl)benzene-1-sulfonamide→(R)-(-)-1-Phenylethylamine→N-tert-Butyl-2-methoxy-5-[(2R)-2-[[(1R)-1-phenylethyl]amino]propyl]benzene-1-sulfonamide→5-[(2R)-2-Aminopropyl]-N-tert-butyl-2-methoxybenzene-1-sulfonamide→(2-Ethoxyphenoxy)acetonitrile→1-Hydroxy-2-ethoxybenzene→2-Chloroacetonitrile→N-tert-Butyl-5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzene-1-sulfonamide→(-)-5-[2(R)-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide
(4-Methoxyphenyl)acetic acid→1-(4-Methoxyphenyl)-2-propanone→Chloridosulfuric acid→2-Methoxy-5-(2-oxopropyl)benzene-1-sulfonyl chloride→1,1-Dimethylethylamine→N-tert-Butyl-2-methoxy-5-(2-oxopropyl)benzene-1-sulfonamide→(R)-(-)-1-Phenylethylamine→N-tert-Butyl-2-methoxy-5-[(2R)-2-[[(1R)-1-phenylethyl]amino]propyl]benzene-1-sulfonamide→5-[(2R)-2-Aminopropyl]-N-tert-butyl-2-methoxybenzene-1-sulfonamide→(2-Ethoxyphenoxy)acetonitrile→1-Hydroxy-2-ethoxybenzene→2-Chloroacetonitrile→N-tert-Butyl-5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzene-1-sulfonamide→(-)-5-[2(R)-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide
(4-Methoxyphenyl)acetic acid→1-(4-Methoxyphenyl)-2-propanone→Chloridosulfuric acid→2-Methoxy-5-(2-oxopropyl)benzene-1-sulfonyl chloride→1,1-Dimethylethylamine→N-tert-Butyl-2-methoxy-5-(2-oxopropyl)benzene-1-sulfonamide→(R)-(-)-1-Phenylethylamine→N-tert-Butyl-2-methoxy-5-[(2R)-2-[[(1R)-1-phenylethyl]amino]propyl]benzene-1-sulfonamide→5-[(2R)-2-Aminopropyl]-N-tert-butyl-2-methoxybenzene-1-sulfonamide→(2-Ethoxyphenoxy)acetonitrile→1-Hydroxy-2-ethoxybenzene→2-Chloroacetonitrile→N-tert-Butyl-5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzene-1-sulfonamide→(-)-5-[2(R)-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide
(4-Methoxyphenyl)acetic acid→1-(4-Methoxyphenyl)-2-propanone→Chloridosulfuric acid→2-Methoxy-5-(2-oxopropyl)benzene-1-sulfonyl chloride→1,1-Dimethylethylamine→N-tert-Butyl-2-methoxy-5-(2-oxopropyl)benzene-1-sulfonamide→(R)-(-)-1-Phenylethylamine→N-tert-Butyl-2-methoxy-5-[(2R)-2-[[(1R)-1-phenylethyl]amino]propyl]benzene-1-sulfonamide→5-[(2R)-2-Aminopropyl]-N-tert-butyl-2-methoxybenzene-1-sulfonamide→(2-Ethoxyphenoxy)acetonitrile→1-Hydroxy-2-ethoxybenzene→2-Chloroacetonitrile→N-tert-Butyl-5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzene-1-sulfonamide→(-)-5-[2(R)-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide
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