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CAS 80494-75-3
ethyl 2-(4-(chloromethyl)phenoxy)acetate
Codes: BAZE-004
Application context (from source-drug indications)
Oestrogen deficiency syndromeConjugated Estrogens/Bazedoxifene AcetateOsteoporosisConjugated Estrogens/Bazedoxifene AcetateVasomotor symptomsConjugated Estrogens/Bazedoxifene AcetateNon-invasive ductal carcinomaConjugated Estrogens/Bazedoxifene AcetateAnxietyConjugated Estrogens/Bazedoxifene AcetateMenopausal symptomsConjugated Estrogens/Bazedoxifene AcetatePostmenopausal osteoporosisBazedoxifene AcetateBreast cancerBazedoxifene AcetateOsteoporosisBazedoxifene AcetateMenopausal symptomsBazedoxifene Acetate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Conjugated Estrogens/Bazedoxifene Acetate | Tier C — Watch / trade | - |
| Bazedoxifene Acetate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-(benzyloxy)aniline hydrochloride→1-(4-(benzyloxy)phenyl)-2-bromopropan-1-one→5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole→ethyl 2-(4-(chloromethyl)phenoxy)acetate→ethyl 2-(4-((5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)methyl)phenoxy)acetate→2-(4-((5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)methyl)phenoxy)ethanol→5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(4-(2-bromoethoxy)benzyl)-3-methyl-1H-indole→azepane→1-(4-(2-(azepan-1-yl)ethoxy)benzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole
4-(benzyloxy)aniline hydrochloride→1-(4-(benzyloxy)phenyl)-2-bromopropan-1-one→5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole→ethyl 2-(4-(chloromethyl)phenoxy)acetate→ethyl 2-(4-((5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)methyl)phenoxy)acetate→2-(4-((5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indol-1-yl)methyl)phenoxy)ethanol→5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-1-(4-(2-bromoethoxy)benzyl)-3-methyl-1H-indole→azepane→1-(4-(2-(azepan-1-yl)ethoxy)benzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole
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