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CAS 80761-61-1
4-oxo-1,4-dihydroquinoline-3-carbonyl chloride
Codes: IVAC-015
Application context (from source-drug indications)
Cystic fibrosisIvacaftorChronic bronchitisIvacaftorChronic obstructive pulmonary diseaseIvacaftorSinusitisIvacaftor
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Ivacaftor | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2,4-di-tert-butylphenol→ethyl carbonochloridate→2,4-di-tert-butylphenyl ethyl carbonate→2,4-di-tert-butyl-5-nitrophenyl ethyl carbonate→5-amino-2,4-di-tert-butylphenyl ethyl carbonate→4-oxo-1,4-dihydroquinoline-3-carbonyl chloride→2,4-di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl ethyl carbonate
Intermediates available on this site
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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.